Trends in nano-antimicrobial therapy for severe liver disease with infection
10.3969/j.issn.1001-5256.2023.03.036
- VernacularTitle:重症肝病合并感染的纳米抗菌治疗趋势
- Author:
Zhenqun LUO
1
,
2
;
Xinhua LUO
2
Author Information
1. School of Clinical Medicine, Zunyi Medical University, Zunyi, Guizhou 563000, China
2. Department of Infectious Diseases, Guizhou Provincial People's Hospital, Guiyang 550000, China
- Publication Type:Review
- Keywords:
Liver Diseases;
Infection;
Nanoparticles
- From:
Journal of Clinical Hepatology
2023;39(3):713-717
- CountryChina
- Language:Chinese
-
Abstract:
Severe liver disease with infection has always been a key and difficult point in clinical treatment. Through continuous exploration of nanomaterials, researchers have found that nanomaterials can achieve targeted antibacterial and immunomodulatory effects due to their special physicochemical properties. With reference to recent articles and advances, this article reviews the possible mechanisms of nano-therapies for severe liver disease with infection from the aspects of targeted antibacterial effect of nanomaterials without antibiotics, targeted antibacterial effect of nano-drug delivery systems, and targeted immunomodulatory therapy, so as to provide new treatment strategies for the prevention and treatment of severe liver disease with infection in clinical practice.
