Association of folic acid with the development and progression of liver cancer
10.3969/j.issn.1001-5256.2023.03.033
- VernacularTitle:叶酸与肝癌发生发展的关系
- Author:
Yingwen LI
1
,
2
,
3
;
Li SHI
1
,
2
,
3
;
Min LIU
2
,
3
;
Hao YUAN
2
,
3
;
Ya ZHENG
2
,
3
;
Yuping WANG
2
,
3
;
Qinghong GUO
2
,
3
Author Information
1. The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China
2. Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, China
3. Gansu Key Laboratory of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, China
- Publication Type:Review
- Keywords:
Liver Neoplasms;
Folic Acid;
DNA Methylation;
Therapeutics
- From:
Journal of Clinical Hepatology
2023;39(3):693-698
- CountryChina
- Language:Chinese
-
Abstract:
So far, liver cancer is still a highly malignant tumor with a high incidence rate in China, and it seriously affects the life and health of Chinese people. Previous studies have shown that the development of liver cancer is associated with various factors such as virus, smoking, drinking, and nonalcoholic fatty liver disease. With continuous exploration, more and more studies have pointed out that nutritional factors and living environment are associated with the development and progression of liver cancer. Folic acid is a necessary nutrient for cell growth and reproduction, and its level in human body has an impact on the growth of tumor cells and is closely associated with liver cancer. This article reviews the research advances in the association between folic acid and liver cancer in recent years, so as to provide new reference and basis for the prevention and treatment of liver cancer.