Role of serum Golgi protein 73 in nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2023.03.028
- VernacularTitle:血清高尔基体蛋白73在非酒精性脂肪性肝病中的作用
- Author:
Hang ZHANG
1
;
Jinchun LIU
2
Author Information
1. Graduate School of Shanxi Medical University, Taiyuan 030001, China
2. Department of Gastroenterology, The First Hospital of Shanxi Medical University, Taiyuan 030001, China
- Publication Type:Review
- Keywords:
Golgi Protein 73;
Non-alcoholic Fatty Fiver Disease;
Liver Cirrohosis;
Serum Biomarker
- From:
Journal of Clinical Hepatology
2023;39(3):657-662
- CountryChina
- Language:Chinese
-
Abstract:
Golgi protein 73 (GP73) is a Golgi transmembrane protein that can be released into blood by cleavage. An increasing number of studies have shown that the increase in serum GP73 is closely associated with the development and progression of nonalcoholic fatty liver disease (NAFLD) and serum GP73 is expected to be used as a potential serological marker for the diagnosis and assessment of NAFLD. This article reviews the research advances in serum GP73 in NAFLD and analyzes its potential mechanism of action, so as to provide new options for the therapeutic targets of NAFLD.
