Association between Serum HBeAg Status and Tuberculosis Infection.
- Author:
Jang Rak KIM
1
;
Jung Han PARK
Author Information
1. Department of Preventive Medicine and Public Health, Kyungpook National University College of Medicine, Korea.
- Publication Type:Original Article
- MeSH:
Asian Continental Ancestry Group;
Cohort Studies;
Gyeongsangbuk-do;
Hepatitis B e Antigens*;
Humans;
Inpatients;
Medical Records;
Nuclear Medicine;
Odds Ratio;
Tuberculosis*
- From:Korean Journal of Preventive Medicine
1989;22(1):65-70
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To examine the association between serum HBeAg status and tuberculosis infection, we reviewed medical records of 579 inpatients who had serum HBeAg test with RIA method at the Department of Nuclear Medicine of Kyungpook University Hospital from January 1, 1985 to December 31, 1987. HBeAg positive patients had lower tuberculosis infection rate (5.0%) than that of HBeAg negative patients(9.8%) and the odds ratio of HBeAg associated with tuberculosis was 0.48(95% C.I.:0.22-1.08). Similar relationship was found in the patients of hepatobiliary diseases; tuberculosis infection rate was 4.4% in HBeAg positive patients, 8.1% in HBeAg negative patients, and the odds ratio was 0.52(95% C.I.:0.17-1.35). Although the association did not reach the statistical significance level of 0.05, the negative association was consistent with other study done on Southeast Asian population of Philadelphia. A cohort study in general population is warranted to confirm above findings because of the limitations on hopital-based data.