Can green tea extract cause specific liver injury?——Discussion of the latest US guidelines on drug-induced liver injury
10.3969/j.issn.1001-5256.2023.03.007
- VernacularTitle:绿茶提取物可致特异质型肝损伤？——与美国最新版药物性肝损伤指南商榷
- Author:
Yunjuan GAO
1
,
2
;
Xu ZHAO
1
;
Jingxiao ZHU
1
,
3
;
Zhaofang BAI
1
;
Jiabo WANG
4
;
Xiaohe XIAO
1
Author Information
1. Senior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China
2. School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
3. National Cancer Center/National Clinical Research Center for Cancer/Hebei Cancer Hospital, Chinese Academy of Medical Sciences, Langfang, Hebei 065001, China
4. School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China
- Publication Type:Academic Contention
- Keywords:
Chemical and Drug Induced Liver Injury;
Catecholamines;
Green Tea Extract
- From:
Journal of Clinical Hepatology
2023;39(3):523-526
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the potential hepatotoxicity of green tea extract (GTE) has attracted more and more attention. With reference to the current studies on liver injury caused by GTE and the latest drug hepatotoxicity classification, this article systematically elaborates on the objectivity and causal mechanisms of liver injury caused by GTE. Based on the main risk factors for liver injury caused by GTE, this article also proposes recommendations for safe and rational use of such products, so as to provide valuable insights for in-depth research on the mechanism of liver injury caused by GTE and risk prevention and control, and meanwhile, it also provides an important reference for the therapeutic use of GTE to improve health conditions.
