Active Mechanism of Nogo and Intervention to Nogo Receptor (review)
- VernacularTitle:Nogo的作用机制和受体干预
- Author:
Zhanbin LU
;
Laiqing SUN
;
Xian CHEN
;
Lanze LIU
;
Ligong WANG
- Publication Type:Journal Article
- Keywords:
Nogo receptor, spinal cord injury, axonal, regeneration, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(8):710-712
- CountryChina
- Language:Chinese
-
Abstract:
Nogo receptor is specific inhibiting factor conjuncted with myelin of central nervous system(CNS).After spinal cord injury,oligodendroglial cell and Nogo-A released from myelin inside cells inhibited the axonal regeneration.To analyze the intervention for Nogo receptor through molecule outside cell,information inside cell and gene,make clearing the inhibiting action of myelin-associated inhibiting factor-1,provide new thoughts and methods about axonal regeneration after spinal cord injury.
