Mechanisms underlying the toxicity of microplastics to mammals: a review
10.19485/j.cnki.issn2096-5087.2023.04.007
- Author:
ZHAO Qianxiu
;
BAI Yuchao
;
BAI Miao
;
ZHANG Can
;
ZHANG Chuanfu
- Publication Type:Journal Article
- Keywords:
microplastics;
exposure pathway;
toxic mechanism;
oxidative stress;
research progress
- From:
Journal of Preventive Medicine
2023;35(4):303-306
- CountryChina
- Language:Chinese
-
Abstract:
As a new type of environmental pollutants, microplastics are widely distributed in the global ecosystem, and ingestion of microplastics may produce a number of toxic effects. Based on currently available publications, this paper describes the main pathways of exposure to microplastics, and summarizes the toxic mechanisms of microplastics in mammals, including oxidative stress, inflammatory response, immune damage, imbalance of gut microbiota, energy metabolism disorder and DNA damage, so as to provide insights into elucidation of the toxic mechanism mechanisms and health risk assessment of microplastics.
- Full text:哺乳动物微塑料暴露的毒理机制研究进展.pdf
