The Clinical Characteristics and Outcomes of Short-term Treatment in Patients with Recurrent Pulmonary Tuberculosis.
10.4046/trd.2008.64.5.341
- Author:
Seung Soo YOO
1
;
Jee Suk KWON
;
Yeh Rim KANG
;
Jeong Woo LEE
;
Seung Ick CHA
;
Jae Yong PARK
;
Tae Hoon JUNG
;
Chang Ho KIM
Author Information
1. Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea. kimch@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Recurrent pulmonary tuberculosis;
Reinfection;
Relapse
- MeSH:
Humans;
Mycobacterium tuberculosis;
Recurrence;
Sprains and Strains;
Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases
2008;64(5):341-346
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Recurrent pulmonary tuberculosis (TB) can be due to relapse of the original infecting strain or due to reinfection with a new strain of Mycobacterium tuberculosis. We investigated the clinical characteristics and efficacy of short-term treatment (6 months) in patients with recurrent pulmonary TB. METHODS: Twenty-nine patients with recurrent pulmonary TB were compared with control patients who received primary treatment for pulmonary TB with respect to drug sensitivity and outcomes of treatment. RESULTS: Most patients with recurrent pulmonary TB (25 cases, 86.2%) recurred more than 2 years after the completion of previous treatment. Twenty-three patients (82.1%) with recurrent pulmonary TB were sensitive to all anti-tuberculous drugs and a ratio was similar to the drug sensitivities observed in control patients. The outcomes of short-term treatment in patients with drug-sensitive TB were not significantly different between the two groups. CONCLUSION: Recurrent pulmonary TB in the study area was likely due to reinfection with new strains. Thus the short-term treatment of patients with drug-sensitive recurrent pulmonary TB may be successful.(Tuberc Respir Dis 2008;64:341-346)
