Progress in the application of patch materials in cardiovascular surgery.
10.11817/j.issn.1672-7347.2023.220560
- Author:
Rubing SHAO
1
;
Jiehua LI
2
;
Lunchang WANG
2
;
Xin LI
3
;
Chang SHU
4
Author Information
1. Department of Vascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011. 2204170208@csu.edu.cn.
2. Department of Vascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011.
3. Department of Vascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011. lixin1981@csu.edu.cn.
4. Department of Vascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011. shuchang@csu.edu.cn.
- Publication Type:Journal Article
- Keywords:
biomaterials;
cardiovascular surgery;
patch materials;
tissue engineering materials
- MeSH:
Cardiac Surgical Procedures/methods*;
Tissue Engineering;
Heart Ventricles;
Heart Atria;
Treatment Outcome
- From:
Journal of Central South University(Medical Sciences)
2023;48(2):285-293
- CountryChina
- Language:English
-
Abstract:
The cardiovascular patch, served as artificial graft materials to replace heart or vascular tissue defect, is still playing a key role in cardiovascular surgeries. The defects of traditional cardiovascular patch materials may determine its unsatisfactory long-term effect or fatal complications after surgery. Recent studies on many new materials (such as tissue engineered materials, three-dimensional printed materials, etc) are being developed. Patch materials have been widely used in clinical procedures of cardiovascular surgeries such as angioplasty, cardiac atrioventricular wall or atrioventricular septum repair, and valve replacement. The clinical demand for better cardiovascular patch materials is still urgent. However, the cardiovascular patch materials need to adapt to normal coagulation mechanism and durability, promote short-term endothelialization after surgery, and inhibit long-term postoperative intimal hyperplasia, its research and development process is relatively complicated. Understanding the characteristics of various cardiovascular patch materials and their application in cardiovascular surgeries is important for the selection of new clinical surgical materials and the development of cardiovascular patch materials.
