Advances in interdisciplinary medical and engineering research of intraocular lens surface modifications to prevent posterior capsule opacification.
10.11817/j.issn.1672-7347.2022.220277
- Author:
Yue ZHANG
1
,
2
;
Jian JIANG
1
,
3
Author Information
1. Eye Center of Xiangya Hospital, Central South University
2. Hunan Key Laboratory of Ophthalmology, Changsha 410008, China. 979245550@qq.com.
3. Hunan Key Laboratory of Ophthalmology, Changsha 410008, China. jiangjianxy@126.com.
- Publication Type:Journal Article
- Keywords:
cataract;
intraocular lens surface modification;
posterior capsule opacification
- MeSH:
Humans;
Capsule Opacification/surgery*;
Lens Implantation, Intraocular;
Cataract/etiology*;
Lens Capsule, Crystalline/surgery*;
Lenses, Intraocular/adverse effects*;
Treatment Outcome;
Postoperative Complications;
Prosthesis Design
- From:
Journal of Central South University(Medical Sciences)
2022;47(12):1754-1762
- CountryChina
- Language:English
-
Abstract:
Posterior capsule opacification (PCO), a common complication after cataract surgery, impacts a patient's long-term visual quality to various degrees. Although a neodymium:yttrium aluminum garnet (Nd:YAG) laser posterior capsulotomy is a very effective treatment, it may lead to a serial of complications. Accordingly, the search for simple, safe, and effective methods to prevent PCO has received widespread attention. Various researchers are committed to the interdisciplinary collaboration between medicine and engineering fields, such as functionalizing the surface of the intraocular lens (IOL) via supercritical fluid impregnation, coating the surface of the IOL, high-concentration drug immersion, and application of a drug delivery system, to effectively reduce the incidence and severity of PCO.
