Difficulties and challenges of pelvic exenteration in locally advanced rectal cancer.
10.3760/cma.j.cn441530-20221123-00488
- Author:
Jin GU
1
;
Qing Kun GAO
2
Author Information
1. Department of Gastrointestinal Surgery III, Peking University Cancer Hospital & Institute, Beijing 100142, China Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing 100144, China.
2. Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing 100144, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Pelvic Exenteration/methods*;
Neoplasm Recurrence, Local/surgery*;
Rectum/surgery*;
Rectal Neoplasms/surgery*;
Pelvis/surgery*;
Treatment Outcome;
Retrospective Studies
- From:
Chinese Journal of Gastrointestinal Surgery
2023;26(3):215-221
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, with advances in pelvic oncology and surgical techniques, surgeons have redefined the boundaries of pelvic surgery. Combined pelvic exenteration is now considered the treatment of choice for some patients with locally advanced and locally recurrent rectal cancer, but it is only performed in a few hospitals in China due to the complexity of the procedure and the large extent of resection, complications, and high perioperative mortality. Although there have been great advances in oncologic drugs and surgical techniques and equipment in recent years, there are still many controversies and challenges in the preoperative assessment of combined pelvic organ resection, neoadjuvant treatment selection and perioperative treatment strategies. Adequate understanding of the anatomical features of the pelvic organs, close collaboration of the clinical multidisciplinary team, objective assessment and standardized preoperative combination therapy creates the conditions for radical surgical resection of recurrent and complex locally advanced rectal cancer, while the need for rational and standardized R0 resection still has the potential to bring new hope to patients with locally advanced and recurrent rectal cancer.
