Diagnostic Value and Safety of Electromagnetic Navigation Bronchoscopy
in Peripheral Pulmonary Lesions: A Meta-analysis.
10.3779/j.issn.1009-3419.2023.102.07
- Author:
Xin SUN
1
;
Yu SU
2
;
Shangyao LI
2
;
Yu TIAN
2
;
Liang ZHAO
1
Author Information
1. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
2. School of Public Health, Capital Medical University, Beijing 100069, China.
- Publication Type:Journal Article
- Keywords:
Diagnostic value;
Electromagnetic navigation bronchoscopy;
Meta-analysis;
Peripheral pulmonary lesions;
Pulmonary nodules
- MeSH:
Humans;
Bronchoscopy;
Lung Neoplasms;
Anesthesia;
China;
Electromagnetic Phenomena
- From:
Chinese Journal of Lung Cancer
2023;26(2):119-134
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:The incidence and mortality of lung cancer have always been at the forefront of malignant tumors. With the development of lung cancer detection techniques, more peripheral pulmonary lesions (PPLs) have been detected. The diagnostic accuracy of procedures for PPLs keeps controversial. This study aims to systematically evaluate the diagnostic value and the safety of electromagnetic navigation bronchoscopy (ENB) in the diagnosis of PPLs.
METHODS:The relevant literatures in the diagnostic yield of PPLs by ENB were systematically retrieved from Wanfang Data Knowledge Service Platform, China National Knowledge Infrastructure, Embase, PubMed, Cochrane Library and Web of Science. The software of Stata 16.0, RevMan 5.4 and Meta-disc 1.4 were used to conduct the meta-analysis.
RESULTS:A total of 54 literatures with 55 studies were included in our meta-analysis. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio of ENB in the diagnosis of PPLs were 0.77 (95%CI: 0.73-0.81), 0.97 (95%CI: 0.93-0.99), 24.27 (95%CI: 10.21-57.67), 0.23 (95%CI: 0.19-0.28) and 104.19 (95%CI: 41.85-259.37), respectively. The area under curve (AUC) was 0.90 (95%CI: 0.87-0.92). Meta-regression and subgroup analyses indicated that the potential heterogeneity resulted from study type, additional localization techniques, sample size, lesion size and type of sedation. The use of additional localization techniques and general anesthesia have improved the diagnostic efficiency of ENB in PPLs. The incidence of adverse reactions and complications associated with ENB was very low.
CONCLUSIONS:ENB provides well diagnostic accuracy and safety.
