Study on the related factors of antiviral treatment in previously reported hepatitis C patients based on the Andersen model.
10.3760/cma.j.cn501113-20221108-00551
- Author:
Peng XU
1
;
Jie Jun YU
2
;
Wan Yue ZHANG
3
;
Dan Dan YANG
4
;
Chuan Wu SUN
5
;
Xing Yun CHEN
6
;
Qing YUAN
2
;
Shao Dong YE
2
;
Liang ZHAO
2
;
Zhong Fu LIU
2
;
Jian LI
2
Author Information
1. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China Shandong Provincial Qianfoshan Hospital, The First Hospital Affiliated with Shandong First Medical University, Jinan 250014, China.
2. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
3. Institute for AIDS/STD Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming 650022, China.
4. Institute for AIDS/STD Control and Prevention, Jiangsu Center for Disease Control and Prevention, Nanjing 210009, China.
5. Department of AIDS/STD Control and Prevention, Xuzhou Center for Disease Control and Prevention, Xuzhou 221000, China.
6. Department of HIV/AIDS Control and Prevention, Wenshan Zhuang and Miao Autonomous Prefecture Center for Disease Control and Prevention, Wenshan 663099, China.
- Publication Type:Journal Article
- Keywords:
Andersen model;
Antiviral therapy;
Associated factors;
Hepatitis C;
Reported HCV-infected patients
- MeSH:
Humans;
Male;
Antiviral Agents/therapeutic use*;
China;
Hepatitis C/drug therapy*;
Hepacivirus;
Logistic Models
- From:
Chinese Journal of Hepatology
2023;31(1):49-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To understand the basic characteristics of previously reported patients with hepatitis C and analyze the related factors affecting their antiviral treatment. Methods: A convenient sampling method was adopted. Patients who had been previously diagnosed with hepatitis C in the Wenshan Prefecture of Yunnan Province and Xuzhou City of Jiangsu Province were contacted by telephone for an interview study. The Andersen health service utilization behavior model and related literature were used to design the research framework for antiviral treatment in previously reported hepatitis C patients. A step-by-step multivariate regression analysis was used in previously reported hepatitis C patients treated with antiviral therapy. Results: A total of 483 hepatitis C patients, aged 51.73 ± 12.06 years, were investigated. The proportion of male, agricultural occupants who were registered permanent residents, farmers and migrant workers was 65.24%, 67.49%, and 58.18%, respectively. Han ethnicity (70.81%), married (77.02%), and junior high school and below educational level (82.61%) were the main ones. Multivariate logistic regression analysis results showed that married patients with hepatitis C (OR = 3.19, 95% CI: 1.93-5.25, compared with unmarried, divorced, and widowed patients) with high school education or above (OR = 2.54, 95% CI: 1.54-4.20, compared with patients with junior high school education or below) were more likely to receive antiviral treatment in the predisposition module. Patients with severe self-perceived hepatitis C in the need factor module (compared with patients with mild self-perceived disease, OR = 3.36, 95% CI: 2.09-5.40) were more likely to receive treatment. In the competency module, the family's per capita monthly income was more than 1,000 yuan (compared with patients with per capita monthly income below 1,000 yuan, OR = 1.59, 95% CI: 1.02-2.47), and the patients had a high level of awareness of hepatitis C knowledge (compared with patients with a low level of knowledge, OR = 1.54, 95% CI: 1.01-2.35), and the family members who knew the patient's infection status (compared with patients with an unknown infection status, OR = 4.59, 95% CI: 2.24-9.39) were more likely to receive antiviral treatment. Conclusion: Different income, educational, and marital statuses are related to antiviral treatment behavior in hepatitis C patients. Family support of hepatitis C patients receiving hepatitis C-related knowledge and their families knowing the infection status is more important in promoting the antiviral treatment of patients, suggesting that in the future, we should further strengthen the hepatitis C knowledge of hepatitis C patients, especially the family support of hepatitis C patients' families in treatment.
