The role of jigsaw karyotype analysis in the teaching of chromosomal recognition.
10.3760/cma.j.cn511374-20220314-00166
- Author:
Jiemei ZHENG
1
;
Yi LAI
Author Information
1. Department of Medical Genetics/Prenatal Diagnosis Center, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University) of the Ministry of Education, Chengdu, Sichuan 610041, China. 12124476@qq.com.
- Publication Type:Journal Article
- MeSH:
Humans;
Karyotyping;
Karyotype;
Cytogenetics;
RNA Splicing;
Software
- From:
Chinese Journal of Medical Genetics
2023;40(3):374-377
- CountryChina
- Language:Chinese
-
Abstract:
Karyotype analysis is the basic method in cytogenetics, and is also recognized as the "gold standard" for diagnosing chromosomal disorders. The teaching and training for traditional karyotyping analysis is time-consuming and even boring. The individual's ability for mastering the chromosome morphology can vary greatly. Therefore, it is necessary to improve the teaching method. On the basis of the traditional method, we have added auxiliary analysis software during the teaching. This type of splicing karyotype teaching has increased the students' interest and improved their ability for karyotyping, allowing them to quickly remember the characteristic bands of chromosomes. Through enhanced memory of a large number of karyotypic images, the students' ability to recognize individual chromosomes has improved.