The impact factors on 5-year survival rate in patients operated with oral cancer.
10.5125/jkaoms.2013.39.5.207
- Author:
Dong Ho GEUM
1
;
Young Chea ROH
;
Sang Yong YOON
;
Hyo Geon KIM
;
Jung Han LEE
;
Jae Min SONG
;
Jae Yeol LEE
;
Dae Seok HWANG
;
Yong Deok KIM
;
Sang Hun SHIN
;
In Kyo CHUNG
;
Uk Kyu KIM
Author Information
1. Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan, Korea. kuksjs@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Oral cancer;
Survival rate;
Neoplasm metastasis;
Recurrence;
TNM classification
- MeSH:
Drinking;
Follow-Up Studies;
Humans;
Lymph Nodes;
Medical Records;
Mouth Neoplasms*;
Neoplasm Metastasis;
Recurrence;
Retrospective Studies;
Smoke;
Smoking;
Surgery, Oral;
Survival Rate*
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2013;39(5):207-216
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: The purpose of this study is to analyze clinical impact factors on the survival rate, and to acquire basic clinical data for the diagnosis of oral cancer, for a determination of the treatment plan with long-term survival in oral cancer patients. MATERIALS AND METHODS: Through a retrospective review of the medical records, the factors for long-term survival rate were analyzed. Thirty-seven patients, among patient database with oral cancer treated in the Department of Oral and Maxillofacial Surgery at Pusan National University Hospital within a period from March 1998 to March 2008, were selected within the study criteria and were followed-up for more than 5 years. The analyzed factors were gender, age, drinking, smoking, primary tumor site, type of cancer, TNM stage, recurrence of affected region, and metastasis of cervical lymph node. The 5-year survival rate on the impact factors was calculated statistically using the Kaplan-Meier method. RESULTS: By classification of clinical TNM at the 1st visit, there were 11 (29.7%) cases for stage I, 11 (29.7%) cases for stage II, 3 (8.1%) cases for stage III, and 12 (32.5%) cases for stage IV. The 5-year survival rate of total oral cancer patients after the operation were 75.7%, pathological TNM stage related 5-year survival rate were as follows: stage I 90.0%, stage II 81.8%, stage III 100% and stage IV 45.5%; in which the survival rate difference by each stage was significantly observed. The recurrence of cervical lymph node was the significant impact factor for the survival rate, because only 30.0% the survival rate in recurrent cases existed. During the follow-up, there were 15 (40.5%) patients with confirmed recurrence, and the 5-year survival rate of these patients was decreased as 46.7%. CONCLUSION: The classification of clinical and pathological TNM stage, local recurrence after surgery, and metastasis of cervical lymph node after surgery were analyzed as the 3 most significant factors.
