Research progress of tunneling nanotube in bone biology.
10.3760/cma.j.cn112144-20221102-00565
- Author:
Jin Biao QIANG
1
;
Xiao Ling WANG
1
;
Xue Ying BAI
1
;
Xin Yi FAN
1
;
Ce SHI
1
Author Information
1. Department of Oral Pathology, Hospital of Stomatology, Jilin University & Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun 130021, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Bone and Bones;
Nanotubes;
Osteoclasts;
Biology;
Cell Communication/physiology*
- From:
Chinese Journal of Stomatology
2023;58(1):86-91
- CountryChina
- Language:Chinese
-
Abstract:
Tunneling nanotube (TNT) is a newly discovered communication mode between animal cells in recent years, which have important physiological and pathological significance. However, the role of TNT in bone biology is still unclear. At present, there are many reports about tunneling nanotubes in bone marrow mesenchymal stem cells, osteoclast precursor cells, osteoblasts and immune cells. This review describes the research advances of TNT and its research progress in bone biology. It looks forward to the research direction of TNT in oral and maxillofacial bone development and bone biology, to provide new strategies for the maintenance of bone homeostasis and the treatment of bone diseases.
