Research progress of thyroid hormone in pulmonary fibrosis.
10.3760/cma.j.cn121094-20210727-00377
- VernacularTitle:甲状腺激素在肺纤维化中的作用和机制研究进展
- Author:
Bao Yan LIU
1
;
Yong WANG
1
;
Yan LIU
1
;
Juan LI
1
;
Ping CUI
1
;
Jin HE
1
Author Information
1. Shandong Academy of Occupational Health and Occupational Medicine (Shandong Province Hospital of Occupational Diseases Hospital of Shandong First Medical University) , Jinan 250062, China.
- Publication Type:Journal Article
- Keywords:
Mechanism;
Pulmonary fibrosis;
Silicosis;
Therapy;
Thyroid hormone
- MeSH:
Humans;
Pulmonary Fibrosis/pathology*;
Lung/pathology*;
Silicosis;
Lung Diseases, Interstitial;
Fibroblasts;
Thyroid Hormones;
Fibrosis
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2023;41(1):62-66
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary fibrosis is end-stage of variety of heterogeneous interstitial lung disease, characterizedby excessive proliferation of fibroblasts and extracellular matrix deposition and destruction of lung parenchyma. Thyroid and lung are derived from the same endodermal cells, thyroid hormone affect the occurrence、development and prognosis of the chronic obstructive pulmonary disease, lung cancer and other lung diseases, This article reviews the role and mechanism of thyroid hormone in pulmonary fibrosis in order to provide new idea for the study of the role and mechanism of thyroid hormone in silicosis.
