6 Cases of Hansen's Disease(New case & Relapse).
- Author:
Jong Pill KIM
1
;
Yeon Sil KIM
Author Information
1. Institute for Leprosy Research, Korean Hansen Welfare Association, Korea. dr_jpkim@hotmail.com
- Publication Type:Case Report
- Keywords:
Leprosy;
New case;
Relapse
- MeSH:
Biopsy;
Emigrants and Immigrants;
Enzyme-Linked Immunosorbent Assay;
Humans;
Lepromin;
Leprosy;
Recurrence;
Skin
- From:Korean Leprosy Bulletin
2008;41(1):37-45
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In 2007, we find 3 new cases and 3 relapse cases, diagnosis by the clinical finding, skin smear, skin biopsy, lepromin test, ELISA for PGL-I antibody, and DNA-PCR. The results obtained were summarized as follows: 1. In 3 new cases, 2 Koreans are 70 and 79 years old, one foreigner (Filipino) is 38 years old, mean BI is 2.8, and mean O.D. of PGL-I antibody is 0.22, and numbers of TTC repeat are 10(Korean), 11(Korean), and 12(Filipino), and of GACATC repeats are 4(2 Koreans) and 3(1 foreigner/ Filipino). All new cases have no mutation of folP1 & rpoB gene. 2. In 3 relapse cases, the mean age is 56.8, mean BI is 5.6+, and mean O.D. of PGL-I antibody is 0.70, and numbers of TTC repeat are 11(2 cases), and 12(1 case), and of GACATC repeats are 4(all 3 Koreans). Among 3 relapse cases, 2 cases have the mutation of folP1 gene and 2cases have the mutationo frpoB gene, especially one case have the mutation of both folP1 & rpoB gene.
