Rapid identification and differential markers of Curcumae Radix decoction pieces of different sources based on Heracles Neo ultra-fast gas phase electronic nose.
10.19540/j.cnki.cjcmm.20221203.301
- Author:
Ming-Xuan LI
1
;
Yu-Wen QIN
1
;
Yu LI
1
;
Jiu-Ba ZHANG
1
;
De JI
1
;
Ling-Yun QU
1
;
Jing-Wen GONG
1
;
Ao-Meng JIA
1
;
Chun-Qin MAO
2
;
Tu-Lin LU
2
Author Information
1. School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210023,China.
2. School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210023,China Jiangsu Provincial Engineering Research Center of TCM External Medication Development and Application Nanjing 210023,China Traditional Chinese Medicine Processing Technology Inheritance Base of the State Administration of Traditional Chinese Medicine Nanjing 210023,China.
- Publication Type:Journal Article
- Keywords:
Curcumae Radix decoction pieces;
diffe-rential markers;
multiple sources;
odor fingerprint;
rapid identification;
ultra-fast gas phase electronic nose
- MeSH:
Drugs, Chinese Herbal/analysis*;
Electronic Nose;
China;
Plant Roots/chemistry*;
Limonene/analysis*;
Chromatography, High Pressure Liquid
- From:
China Journal of Chinese Materia Medica
2023;48(6):1518-1525
- CountryChina
- Language:Chinese
-
Abstract:
Since Curcumae Radix decoction pieces have multiple sources, it is difficult to distinguish depending on traditional cha-racters, and the mixed use of multi-source Curcumae Radix will affect its clinical efficacy. Heracles Neo ultra-fast gas phase electronic nose was used in this study to quickly identify and analyze the odor components of 40 batches of Curcumae Radix samples from Sichuan, Zhejiang, and Guangxi. Based on the odor fingerprints established for Curcumae Radix decoction pieces of multiple sources, the odor components was identified and analyzed, and the chromatographic peaks were processed and analyzed to establish a rapid identification method. Principal component analysis(PCA), discriminant factor analysis(DFA), and soft independent modeling cluster analysis(SIMCA) were constructed for verification. At the same time, one-way analysis of variance(ANOVA) combined with variable importance in projection(VIP) was employed to screen out the odor components with P<0.05 and VIP>1, and 13 odor components such as β-caryophyllene and limonene were hypothesized as the odor differential markers of Curcumae Radix decoction pieces of diffe-rent sources. The results showed that Heracles Neo ultra-fast gas phase electronic nose can well analyze the odor characteristics and rapidly and accurately discriminate Curcumae Radix decoction pieces of different sources. It can be applied to the quality control(e.g., online detection) in the production of Curcumae Radix decoction pieces. This study provides a new method and idea for the rapid identification and quality control of Curcumae Radix decoction pieces.
