A new dihydrostilbene from aerial part of Cannabis sativa.
10.19540/j.cnki.cjcmm.20220406.201
- Author:
Zhi-Hua LIU
1
;
Jin-Lan WANG
2
;
Ying-Nan ZHAO
2
;
Jun LI
2
;
Zhi-Chun SHI
2
;
Dan WANG
2
;
Ming ZHAO
2
;
Shu-Jun ZHANG
2
Author Information
1. College of Chemistry and Chemical Engineering, Qiqihar University Qiqihar 161006, China.
2. College of Chemistry and Chemical Engineering, Qiqihar University Qiqihar 161006, China Heilongjiang Industrial Hemp Processing Technology Innovation Center Qiqihar 161006, China Technology Innovation Center of Industrial Hemp for State Market Regulation Qiqihar 161006, China.
- Publication Type:Journal Article
- Keywords:
Cannabis sativa;
cannabinoids;
dihydrostilbene;
octadecenoic acid
- MeSH:
Cannabis;
Biological Products;
Esters;
Dihydrostilbenoids;
Plant Components, Aerial
- From:
China Journal of Chinese Materia Medica
2023;48(4):985-992
- CountryChina
- Language:Chinese
-
Abstract:
The present study investigated the chemical constituents in the aerial part of Cannabis sativa. The chemical constituents were isolated and purified by silica gel column chromatography and HPLC and identified according to their spectral data and physicochemical properties. Thirteen compounds were isolated from the acetic ether extract of C. sativa and identified as 3',5',4″,2-tetrahydroxy-4'-methoxy-3-methyl-3″-butenyl p-disubstituted benzene ethane(1), 16R-hydroxyoctadeca-9Z,12Z,14E-trienoic acid methyl ester(2),(1'R,2'R)-2'-(2-hydroxypropan-2-yl)-5'-methyl-4-pentyl-1',2',3',4'-tetrahydro-(1,1'-biphenyl)-2,6-diol(3), β-sitosteryl-3-O-β-D-glucopyranosyl-6'-O-palmitate(4), 9S,12S,13S-trihydroxy-10-octadecenoate methyl ester(5), benzyloxy-1-O-β-D-glucopyranoside(6), phenylethyl-O-β-D-glucopyranoside(7), 3Z-enol glucoside(8), α-cannabispiranol-4'-O-β-D-glucopyranose(9), 9S,12S,13S-trihydroxyoctadeca-10E,15Z-dienoic acid(10), uracil(11), o-hydroxybenzoic acid(12), and 2'-O-methyladenosine(13). Compound 1 is a new compound, compound 3 is a new natural product, and compounds 2, 4-8, 10, and 13 were isolated from Cannabis plant for the first time.
