Chemical constituents from leaves of Craibiodendron yunnanense.
10.19540/j.cnki.cjcmm.20220608.201
- Author:
Man WANG
1
;
Ya-Nan WANG
1
;
Hai-Qiang WANG
1
;
Wan-Qi YANG
1
;
Shuang-Gang MA
1
;
Yong LI
1
;
Jing QU
1
;
Yun-Bao LIU
1
;
Shi-Shan YU
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100050, China.
- Publication Type:Journal Article
- Keywords:
Craibiodendron;
Craibiodendron yunnanense;
chemical constituent;
cytotoxic activity
- MeSH:
Quercetin;
Ericaceae;
Plant Leaves;
Catechin;
Chromatography, High Pressure Liquid
- From:
China Journal of Chinese Materia Medica
2023;48(4):978-984
- CountryChina
- Language:Chinese
-
Abstract:
The present study investigated the chemical constituents from the leaves of Craibiodendron yunnanense. The compounds were isolated and purified from the leaves of C. yunnanense by a combination of various chromatographic techniques including column chromatography over polyamide, silica gel, Sephadex LH-20, and reversed-phase HPLC. Their structures were identified by extensive spectroscopic analyses including MS and NMR data. As a result, 10 compounds, including melionoside F(1), meliosmaionol D(2), naringenin(3), quercetin-3-O-α-L-arabinopyranoside(4), epicatechin(5), quercetin-3'-glucoside(6), corbulain Ib(7), loliolide(8), asiatic acid(9), and ursolic acid(10), were isolated. Compounds 1 and 2 were two new compounds, and compound 7 was isolated from this genus for the first time. All compounds showed no significant cytotoxic activity by MTT assay.
