Research progress on chemical constituents of Schisandra chinensis and its effect on nonalcoholic fatty liver disease.
10.19540/j.cnki.cjcmm.20220616.201
- Author:
Xin-Lu MU
1
;
Bin LI
1
;
Yu-Cen ZOU
1
;
Jiu-Shi LIU
1
;
Ben-Gang ZHANG
1
;
Pei-Gen XIAO
1
;
Hai-Tao LIU
1
Author Information
1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education,Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100193, China.
- Publication Type:Journal Article
- Keywords:
Schisandra chinensis;
chemical constituents;
nonalcoholic fatty liver disease
- MeSH:
Non-alcoholic Fatty Liver Disease;
Schisandra;
Insulin Resistance;
Lignans
- From:
China Journal of Chinese Materia Medica
2023;48(4):861-878
- CountryChina
- Language:Chinese
-
Abstract:
Schisandra chinensis, a traditional Chinese medicinal herb, is rich in chemical constituents, including lignans, triterpenes, polysaccharides, and volatile oils. Clinically, it is commonly used to treat cardiovascular, cerebrovascular, liver, gastrointestinal, and respiratory diseases. Modern pharmacological studies have shown that S. chinensis extract and monomers have multiple pharmacological activities in lowering liver fat, alleviating insulin resistance, and resisting oxidative stress, and have good application prospects in alleviating nonalcoholic fatty liver disease(NAFLD). Therefore, this study reviewed the research progress on chemical constituents of S. chinensis and its effect on NAFLD in recent years to provide references for the research on S. chinensis in the treatment of NAFLD.
