Traditional Chinese medicine therapy for rheumatoid arthritis: a review.
10.19540/j.cnki.cjcmm.20220922.502
- Author:
Cen CHANG
1
;
Run-Run ZHANG
2
;
Yi-Ming SHI
1
;
Dong-Yi HE
1
Author Information
1. Department of Arthritis, Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine Shanghai 200052, China Arthritis Institute of Integrative Medicine, Shanghai Institute of Integrative Medicine Shanghai 200052, China Shanghai University of Traditional Chinese Medicine Shanghai 200052, China.
2. the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine Ji'nan 250002, China.
- Publication Type:Journal Article
- Keywords:
research progress;
rheumatoid arthritis;
traditional Chinese medicine therapy
- MeSH:
Humans;
Medicine, Chinese Traditional;
Drugs, Chinese Herbal/therapeutic use*;
Arthritis, Rheumatoid/drug therapy*;
Antirheumatic Agents/therapeutic use*;
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use*
- From:
China Journal of Chinese Materia Medica
2023;48(2):329-335
- CountryChina
- Language:Chinese
-
Abstract:
Rheumatoid arthritis(RA) is an autoimmune disease that seriously affects the physical and mental health of patients, but its pathogenesis is still unclear. At present, clinical treatment drugs include conventional synthetic disease modifing anti-rheumatic drugs(csDMARDs), nonsteroid anti-inflammtory drugs(NSAIDs), hormones, small molecule targeted drugs, biological agents, etc. These drugs can relieve the clinical symptoms of most patients with RA to a certain extent, but there are still many limitations, such as drug adverse reactions and individual differences in drug efficacy. Therefore, the research on drug treatment targets and the development of low-toxicity drugs helps further improve the precise prevention, diagnosis, and treatment of RA. There is an urgent need for efficient and low-toxic treatments to delay the clinical progress of RA. As a treasure of Chinese culture, traditional Chinese medicine(TCM) is widely used as an alternative therapy in the treatment of various diseases, and has a significant clinical efficacy. TCM therapy(including monomer traditional Chinese medicine, classical compounds, and non-drug therapies) has a significant curative effect on RA. Based on the literature research in recent years, this paper reviewed the clinical and mechanism research of TCM therapy in the treatment of RA, and provided more in-depth thinking for the wide application of TCM therapy in clinical practice.
