Research Progress in Pathogenesis of Hypertension in Acute Intermittent Porphyria.
10.3881/j.issn.1000-503X.14571
- Author:
Qing-Yang LI
1
;
Yi REN
2
;
Jian-Hong WANG
3
;
Jing YANG
2
Author Information
1. The First Clinical Medical College,Shanxi Medical University,Taiyuan 030001,China.
2. Department of Endocrinology,The First Hospital of Shanxi Medical University,Taiyuan 030001,China.
3. Department of Neurology,Shanxi Provincial Cardiovascular Hospital,Taiyuan 030024,China.
- Publication Type:Journal Article
- Keywords:
acute intermittent porphyria;
hypertension;
porphyria;
secondary hypertension
- MeSH:
Humans;
Porphyria, Acute Intermittent;
Blood Glucose;
Hypertension/etiology*;
Inflammation;
Life Style
- From:
Acta Academiae Medicinae Sinicae
2023;45(1):129-133
- CountryChina
- Language:Chinese
-
Abstract:
Acute intermittent porphyria (AIP) has complicated clinical manifestations and is often accompanied by hypertension.AIP may cause hypertension through adrenergic effect,heme deficiency,inflammation,inappropriate secretion of antidiuretic hormone,toxicity of delta-aminolevulinic acid(ALA,aporphyrin precursor),and elevated serum glucose level.The prevention and treatment strategies for AIP accompanied with hypertension mainly include the controlling of porphyria attacks,application of antihypertensive drugs,lifestyle intervention,and management of latent AIP patients.
