Research Progress on Epigenetics in Endometriosis.
10.3881/j.issn.1000-503X.14739
- Author:
Rui-Hui LU
1
;
Jing-Wen ZHU
1
;
Qing XUE
1
Author Information
1. Department of Gynecology and Obstetrics,Peking University First Hospital,Beijing 100034,China.
- Publication Type:Journal Article
- Keywords:
DNA methylation;
endometriosis;
epigenetics;
histone modification;
non-coding RNA
- MeSH:
Female;
Humans;
Endometriosis/genetics*;
Epigenesis, Genetic;
DNA Methylation;
Protein Processing, Post-Translational
- From:
Acta Academiae Medicinae Sinicae
2023;45(1):124-128
- CountryChina
- Language:Chinese
-
Abstract:
Epigenetics refers to heritable changes in gene expression and function without alterations in gene sequences,including DNA methylation,histone modification,and non-coding RNAs.Endometriosis is a benign gynecological disease that affects the fertility and health of reproductive-age women,the etiology of which remains unclear.The recent studies have demonstrated that epigenetics plays a key role in the occurrence and development of endometriosis.This article reviews the research progress in the regulatory mechanism and application of epigenetics in endometriosis.
