- Author:
Tao YE
1
;
Qi XIANG
1
;
Yan YANG
1
;
Yadong HUANG
1
Author Information
- Publication Type:Journal Article
- Keywords: biotechnology; collagen; development and application; research progress
- MeSH: Animals; Collagen/analysis*; Tissue Engineering/methods*; Extracellular Matrix/metabolism*; Biomimetic Materials/chemistry*; Bone and Bones; Tissue Scaffolds; Mammals/metabolism*
- From: Chinese Journal of Biotechnology 2023;39(3):942-960
- CountryChina
- Language:Chinese
- Abstract: Collagen, which widely exists in skin, bone, muscle and other tissues, is a major structural protein in mammalian extracellular matrix. It participates in cell proliferation, differentiation, migration and signal transmission, plays an important role in tissue support and repair and exerts a protective effect. Collagen is widely used in tissue engineering, clinical medicine, food industry, packaging materials, cosmetics and medical beauty due to its good biological characteristics. This paper reviews the biological characteristics of collagen and its application in bioengineering research and development in recent years. Finally, we prospect the future application of collagen as a biomimetic material.