Research progress on the modulation mechanism of electroacupuncture for learning and memory impairment after ischemic stroke.
10.13703/j.0255-2930.20220304-k0003
- Author:
Nan-Nan ZHAO
1
;
Yan-Jie LI
2
,
3
;
He-Wei QIN
2
,
3
;
Hui-Min DING
1
;
Xiao-Qiong HUA
1
;
Bo-Chao ZHU
1
;
Yu-Pu WANG
1
Author Information
1. School of Rehabilitation Medicine, Henan University of TCM, Zhengzhou 450046, China.
2. School of Rehabilitation Medicine, Henan University of TCM, Zhengzhou 450046, China
3. Rehabilitation Department, Henan Provincial Hospital of TCM, Zhengzhou 450046.
- Publication Type:Journal Article
- Keywords:
electroacupuncture;
ischemic stroke;
learning and memory impairment;
signaling pathway
- MeSH:
Humans;
Electroacupuncture;
Ischemic Stroke;
Learning;
Signal Transduction/physiology*
- From:
Chinese Acupuncture & Moxibustion
2023;43(2):239-244
- CountryChina
- Language:Chinese
-
Abstract:
Electroacupuncture may play a role in treatment of learning and memory impairment after ischemic stroke by regulating phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signaling pathway, cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA)/cAMP response element binding protein (CREB) signaling pathway, nerve growth factor (NGF)/tyrosine kinase-A (TrkA) signaling pathway, Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway, Notch signaling pathway, erythropoietin-producing hepatocyte (Eph)/ephrin signaling pathway. The interactions among these pathways should be further explored in treatment of learning and memory impairment after ischemic stroke.
