The advances of allergen component detection in IgE-mediated food allergy.
10.3760/cma.j.cn112150-20220726-00758
- Author:
Hao CHEN
1
;
Rong Fei ZHU
1
;
Xiao Tang LIAO
2
;
Bao Qing SUN
3
Author Information
1. Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
2. Hunan Center for Drug Evaluation and Adverse Reaction Monitoring,Changsha 410013, China.
3. State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Allergens;
Immunoglobulin E;
Food Hypersensitivity/diagnosis*;
Skin Tests
- From:
Chinese Journal of Preventive Medicine
2023;57(3):333-340
- CountryChina
- Language:Chinese
-
Abstract:
There are many types in food allergy, and the most common is mediated by IgE. Currently, the diagnosis of food allergy mainly relied on skin prick test and serum specific IgE of allergen extract, which can not identify cross-sensitization. Component-resolved diagnosis (CRD) can identify the major allergen components and cross-components of food allergens, which plays an important role in dietary guidance, prognosis monitoring and diagnosis of special types of IgE-mediated food allergy. This article enumerates clinical characteristics of the IgE-mediated common food allergies, such as milk, egg and seafood allergy, and special type of food allergy, such as cat pork syndrome, oral allergy syndrome, α-gal syndrome and food-dependent exercise-induced anaphylaxis, summarizes the advances of CRD in these types of IgE-mediated food allergy, in order to provide an evidence for the diagnosis, treatment and prevention of IgE-mediated food allergy.
