Genomic structure of varicella-zoster virus and its vaccine application status.

Author: Jing Bo TAO ¹ ; Bin Bin WAN ¹ ; Jin Hua CHEN ¹ ; Jian Wei JIA ¹ ; Hang CHENG ¹ ; Ling Qiao LOU ¹ ; Shu Ying LUO ¹
Author Information

1. Yiwu Center for Disease Control and Prevention, Yiwu 322000, China.
Publication Type:Journal Article
MeSH: Humans; Herpesvirus 3, Human/genetics*; Herpes Zoster/prevention & control*; Herpes Zoster Vaccine; Chickenpox Vaccine; Genomics
From: Chinese Journal of Preventive Medicine 2023;57(2):286-292
CountryChina
Language:Chinese
Abstract: With the determination of the whole genome sequence of varicella-zoster virus (VZV) virus, the successful breakthrough of infectious cloning technology of VZV, and the emergence of effective preventive vaccines, which have been proven to be effective and safe, varicella has become a disease preventable by specific immunity. This article will review the genomic structure, epidemiological characteristics, and research application progress of varicella vaccine and herpes zoster vaccine of varicella zoster virus to provide reference for primary prevention of the disease.