Significance of preventing developmental origins of diseases in improving population quality.
10.3760/cma.j.cn112150-20220928-00932
- Author:
Li Hao HU
1
;
He Feng HUANG
1
Author Information
1. Obstetrics and Gynecology Hospital, Fudan University/Institute of Reproduction and Development, Fudan University, Shanghai 200090, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Humans;
Epigenesis, Genetic;
Chronic Disease;
Noncommunicable Diseases/genetics*
- From:
Chinese Journal of Preventive Medicine
2023;57(2):154-158
- CountryChina
- Language:Chinese
-
Abstract:
More studies show that various diseases, especially chronic non-infectious diseases, have developmental origin. Developmental origins of diseases are mainly due to gametes and early life development stage being exposed to adverse environment, resulting in abnormal modification of epigenetic and stable inheritance to the adult stage, which could make the risk of various long-term diseases of individuals high. The theory of developmental origin provides a new perspective for the occurrence and development of diseases, and also provides a theoretical basis for disease prevention. Attaching importance to maternal and child health care and life-cycle management is conducive to the prevention of developmental diseases and is of great significance to the improvement of population quality.
