Target Controlled or Intermittent Infusion of Sufentanil during Awake Craniotomy
- VernacularTitle:脑功能区胶质瘤手术唤醒麻醉中持续或间断输注舒芬太尼的影响
- Author:
Hao CHENG
;
Dexiang WANG
;
Ruquan HAN
- Publication Type:Journal Article
- Keywords:
cerebral function zone, glioma, awake anesthesia, sufentanil, respiratory depression
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(7):679-680
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy and safety of the target controlled administration of sufentanil and intermittent sufentanil during awake craniotomy. Methods 40 patients were randomized into target controlled infusion of sufentanil group (n=20) and intermittent sufentanil group (n=20) and compared. Results The hemodynamic parameters were similar in the two groups. However, target controlled infusion of sufentanil was associated with significantly lower respiratory rate （P<0.05）, higher end tidal CO2 （P<0.05）, and higher dosage of sufentanil （P<0.01）, compared with those of intermittent sufentanil. Conclusion Intermittent sufentanil infusion is associated with less respiratory depression than target controlled administration of sufentanil in awake craniotomy.
