A Case of Primary Cutaneous Aspergillosis in a Leukemic Child.
- Author:
Jeong Hoon CHOE
1
;
Jung Hwa LEE
;
Kee Hyung LEE
;
Kwang Chul LEE
Author Information
1. Department of Pediatrics, College of Medicine, Korea University, Seoul Korea.
- Publication Type:Case Report
- Keywords:
Acute lymphoblastic leukemia;
Aspergillus niger;
Skin
- MeSH:
Amphotericin B;
Aspergillosis*;
Aspergillus niger;
Child*;
Child, Preschool;
Debridement;
Drug Therapy;
Follow-Up Studies;
Fungi;
Humans;
Itraconazole;
Male;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Skin;
Ulcer
- From:Korean Journal of Pediatric Hematology-Oncology
1998;5(1):188-193
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 5-year-old boy developed painful erythematous indurated patch at vertex that rapidly progressed to central necrotic ulceration with peripheral granulation after chemotherapy for acute lymphoblastic leukemia. Cultures at the lesion sites demonstrated a fungus, Aspergillus niger, as the etiologic agent. No evidence of involvement of other organs or of systemic dissemination by Aspergillus niger was found. Surgical debridement was performed and the patient received treatment with intravenous Amphotericine B followed by oral itraconazole. No evidence of recurrent fungal infection was noted during several months of follow-up.