Half-Saline Versus Normal-Saline as Irrigation Solutions in Burr Hole Craniostomy to Treat Chronic Subdural Hematomata: A Randomized Clinical Trial
10.13004/kjnt.2022.18.e47
- Author:
Mehdi MAHMOODKHANI
1
;
Mohammad SHARAFI
;
Arman SOURANI
;
Donya Sheibani TEHRANI
Author Information
1. Department of Neurosurgery, Kashani Hospital, School of Medicine, Isfahan University of Medical Sciences, Tehran, Iran
- Publication Type:Clinical Article
- From:Korean Journal of Neurotrauma
2022;18(2):221-229
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objective:This study aimed to evaluate the efficacy and safety of half-saline (HS) serum as an irrigation solution in chronic subdural hematoma (CSDH) surgery using the burr hole craniostomy (BHC) technique.
Methods:This randomized clinical trial was conducted in university hospital referral centers from 2020 to 2021. Sixty-three patients with CSDH eligible for BHC were primarily enrolled. Two patients were excluded because of concurrent stroke. Sixty-one patients were randomly allocated into case (HS=30) and control (normal-saline [NS]=31) groups. HS was used to irrigate the hematoma in the case group and NS was used in the control group. The patients were followed-up. Clinical variables including demographic and medical findings, postoperative computed tomography findings, postoperative complications, hospitalization period, recurrence rate, and functional status measured by the Barthel type B index were recorded.
Results:Forty-six of 61 patients were male (75.4%), and the patients’ mean age was 65.4±16.9 years, with equal distribution between the 2 groups. Postoperative effusion and postoperative hospital stay duration were significantly lower in the HS group than in the NS group (p=0.002 and 0.033, respectively). The postoperative recurrence within 3 months in both groups was approximately equal (6.6%). In terms of functional outcomes and postoperative complications, HS showed similar results to those of NS.
Conclusion:HS as an irrigation fluid in BHC effectively reduced postoperative effusion and hospital stay duration without considerable complications.
