Usefulness of Endoscopic Mucosal Resection for Curative Treatment of Early Gastric Cancer.
- Author:
Dong Hyo HYUN
1
;
Seok JEONG
;
Jin Woo LEE
;
Bong Joo JEONG
;
Sung Tae RYU
;
Chang Kun LEE
;
Myung Sik KIM
;
Kye Sook KWON
;
Don Haeng LEE
;
Pum Soo KIM
;
Hyung Gil KIM
;
Yong Woon SHIN
;
Young Soo KIM
Author Information
1. Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. kimhg@inha.ac.kr
- Publication Type:Original Article ; English Abstract
- Keywords:
Stomach neoplasms;
Early gastric cancer;
Endoscopic mucosal resection
- MeSH:
Aged;
*Endoscopy, Gastrointestinal;
Female;
Gastric Mucosa/*surgery;
Humans;
Male;
Retrospective Studies;
Stomach Neoplasms/pathology/*surgery
- From:The Korean Journal of Gastroenterology
2003;42(6):453-460
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Endoscopic mucosal resection (EMR) has been widely accepted as a curative treatment of early gastric cancer (EGC). The aim of this study was to determine the usefulness and limitations of EMR for treatment of EGC by analyzing our own experience. METHODS: We retrospectively evaluated 51 EGC lesions (45 mucosal and 6 submucosal cancers) from 49 patients who had undergone EMR between Oct. 1997 and Aug. 2002 at Inha Universtiy Hospital. RESULTS: Among 45 lesions of mucosal cancer, enbloc resection was performed in 13 lesions and piecemeal resection in 32 lesions. Complete resection rates of enbloc and piecemeal resection were 84.6% and 43.8%, respectively (p=0.012). Complete resection rate of the lesions smaller than 1 cm in size was 71.4%, 1 to 2 cm in size 52%, and greazter than 2 cm in size 37.5%. Complete resection rates of well, moderately, and poorly differentiated EGC were 59.4%, 71.4%, and 16.7%, respectively (p=0.048). Thirty-three patients underwent a follow-up endoscopy at I month after EMR and two were found to have residual cancers. One patient who had a piecemeal EMR showed cerical and abdominal lymph node metastasis 10 months after EMR. CONCLUSIONS: In selected patients with EGC, EMR can be a curative treatment modality. However, complete resection rate is low in large sized and poorly differentiated EGCs and when piecemeal resection is performed.
