Case of Mycobacterium Massiliense Infection Presenting as Recurrent Pneumonia in Sjogren's Syndrome.
- Author:
Ji Young SEO
1
;
Byung Hee LEE
;
Jang Won LEE
;
Myeong Hee LEE
;
Suk Gyeong O
;
Hyun Myung CHO
;
Chung Won LEE
Author Information
1. Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea. chojfamily@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Nontuberculous mycobacteria;
Mycobacterium massiliense;
Pneumonia;
Sjogren's syndrome
- MeSH:
Adult;
Amikacin;
Cefoxitin;
Clarithromycin;
Female;
Humans;
Korea;
Mycobacterium;
Nontuberculous Mycobacteria;
Pneumonia;
Sequence Analysis;
Sjogren's Syndrome
- From:Korean Journal of Medicine
2012;83(2):243-248
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mycobacterium massiliense is an emerging pathogen that is increasingly reported as a causative agent occurring during medical procedures, at surgical sites, and intramuscularly [1]. Although previously classified as part of M. abscessus, M. massiliense has recently been identified as a new species of rapidly growing nontuberculous mycobacteria [1,3] via a comparative sequence analysis of rpoB and hsp65 [3,5]. However, the clinical manifestations of M. massiliense have not been well characterized. We report here in a case of recurrent pneumonia for 3 years that improved with antibiotic treatment for M. massiliense in a 37-year-old woman with Sjogren's syndrome. The patient showed a substantial response to treatment with a combination of antimicrobial therapies comprising clarithromycin and amikacin without cefoxitin for 6 months. This is the first report of pulmonary infection of M. massiliense with Sjogren's syndrome in Korea.
