A Practical Review of Paraproteinemic Neuropathy
10.46518/kjnmd.2022.14.2.23
- Author:
Joong-Yang CHO
1
Author Information
1. Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine
- Publication Type:Review Article
- From:
Korean Journal of Neuromuscular Disorders
2022;14(2):23-29
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paraproteinemic neuropathy is a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. Most cases are associated with monoclonal gammopathy of undetermined significance. It might also occur in hematologic malignant and nonmalignant conditions. The association between neuropathy and monoclonal gammopathy requires appropriate neurological and hematological investigations. Treatment is mostly based on underlying hematologic disorders. In this review, we provide a clinically practical approach to clinical, laboratory, electrophysiological features and management of patients with paraproteinemic neuropathy.