A case of adrenal gland dependent hyperadrenocorticism with mitotane therapy in a Yorkshire terrier dog.
- Author:
Young Mi LEE
1
;
Byeong Teck KANG
;
Dong in JUNG
;
Chul PARK
;
Ha Jung KIM
;
Ju Won KIM
;
Chae Young LIM
;
Eun Hee PARK
;
Hee Myung PARK
Author Information
1. Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea. parkhee@konkuk.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
adrenal gland tumor;
dog;
hyperadrenocorticism
- MeSH:
Adrenal Gland Neoplasms/complications/diagnosis/drug therapy/*veterinary;
Adrenocortical Hyperfunction/diagnosis/drug therapy/etiology/*veterinary;
Adrenocorticotropic Hormone/blood;
Animals;
Antineoplastic Agents, Hormonal/*therapeutic use;
Dog Diseases/*drug therapy;
Dogs;
Male;
Mitotane/*therapeutic use;
Radiography, Abdominal/veterinary;
Tomography, X-Ray/veterinary
- From:Journal of Veterinary Science
2005;6(4):363-366
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hyperadrenocorticism, a disorder characterized by excessive production of cortisol by the adrenal cortex, is wellrecognized in dogs. A 10-year-old, intact male, Yorkshire terrier dog was evaluated because of corneal ulceration and generalized alopecia. Diagnosis was made based on history taking, clinical signs, physical examination, and results of routine laboratory testing (complete blood count, serum biochemical analysis, and urinalysis). In addition, adrenocorticotropic hormone (ACTH) stimulation test and abdominal ultrasonography were also used to diagnose this case. The patient was diagnosed as adrenal gland neoplasia and medical therapy using the adrenocorticolytic agent, mitotane, was initiated. An ACTH stimulation test was performed after initial therapy. After successful induction was obtained, maintenance therapy with mitotane still continued.
