Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis.
- Author:
Pyung Kil KIM
1
;
Kyo Sun KIM
;
Chul LEE
;
Nan Ae KIM
;
Jae Seung LEE
Author Information
1. Department of Pediatrics, Yonsei university college of medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Glomerulonephritis;
Acute poststreptococcal glomerulonephritis;
Minimal lesion nephrotic syndrome;
Henoch-Schonlein purpura nephritis
- MeSH:
Glomerulonephritis*;
Humans;
Immunoglobulin A;
Immunoglobulin G;
Immunoglobulin M;
Immunoglobulins*;
Nephritis;
Nephrotic Syndrome;
Purpura;
Reference Values
- From:Journal of the Korean Pediatric Society
1981;24(7):652-658
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations were normal limit in minimal lesion nephrotic syndrome. In one-forth of acute poststreptococcal glomerulonephritis and one-half of Henoch-Sch?lein purpura nephritis, serum IgA concentrations were elevated. 3) Serum IgM concentrations were normal in acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. We concluded that serum immunoglobulin concentrations were not useful as an aid in diagnosing glomerulonephritis.
