Clinical outcomes of gastric cancer surgery after liver transplantation
10.4174/astr.2023.104.2.101
- Author:
Sunjoo KIM
1
;
Hyuk-Joon LEE
;
Fadhel ALZAHRANI
;
Jeesun KIM
;
Sa-Hong KIM
;
Sara KIM
;
Yo-Seok CHO
;
Ji-Hyeon PARK
;
Jeong-Moo LEE
;
Seong-Ho KONG
;
Do Joong PARK
;
Kyung-Suk SUH
;
Han-Kwang YANG
Author Information
1. Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Annals of Surgical Treatment and Research
2023;104(2):101-108
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:De novo malignancy is common after liver transplantation (LT); however, there are limited reports on the clinical outcomes of gastric cancer surgery after LT. Our study aimed to investigate the feasibility and safety of gastric cancer surgery after LT.
Methods:Seventeen patients underwent gastric cancer surgery after LT at a single institution between January 2013 and June 2021. We retrospectively collected data on surgical complications, survival, and recurrence status of these cases.
Results:Fifteen patients (88.2%) underwent curative gastrectomy, with 10 open distal (66.7%) and 5 laparoscopic distal (33.3%) gastrectomies. Surgical and severe complication rates were 3 of 15 (20.0%) and 1 of 15 (6.7%), respectively. There were no significant differences between laparoscopic (33.3%) and open surgery (66.7%) in terms of operation time and complication rate. No surgery-related mortalities occurred. Immunosuppressants could be maintained without difficulty, and no suspicious acute rejection was identified during the perioperative period. There was 1 recurrence after curative surgery (recurrence rate, 6.7%), and the 5-year cancer-specific survival rate after curative surgery was 93.3%.
Conclusion:Laparoscopic gastrectomy can be safely done even after LT in terms of postoperative complications and graft safety.
