A Case of Cervical Cancer With Rupture of Pyometra Immediately Before Cancer Treatment and Development of Colouterine and Enterocutaneous Fistulas After Chemoradiotherapy
- VernacularTitle:主治療直前に子宮留膿腫が穿孔し，放射線療法，化学療法後に子宮腸管瘻・腸管皮膚瘻を発症した子宮頸癌の１例
- Author:
Naomi KIMURA
1
;
Yuta KATO
1
;
Minami HASHIMOTO
1
;
Keika YAMAUCHI
1
;
Emi KONDO
1
;
Mari SHIBATA
1
;
Shoko KOZAKI
1
;
Teruko MIZUNO
1
;
Yasushi MATSUKAWA
1
;
Kyoko KUMAGAI
1
;
Masahiro IKEUCHI
1
;
Kazuhiro HIGUCHI
1
Author Information
- From:Journal of the Japanese Association of Rural Medicine 2022;71(4):348-356
- CountryJapan
- Language:Japanese
- Abstract: The patient was a 68-year-old woman who was diagnosed with stage IIIA cervical cancer and pyometra. Concurrent chemoradiotherapy was planned. She was admitted to our hospital 3 weeks after the initial examination due to vaginal bleeding and worsening of lower abdominal pain. On hospital day 5, she developed a fever, and free gas in the peritoneal cavity and ascites were confirmed by contrast-enhanced computed tomography. Emergency surgery was performed for suspected generalized peritonitis attributed to perforation in the digestive tract or uterus. A large amount of purulent ascites and 2 perforations in the anterior wall of the uterus, but none in the digestive tract, were observed. Peritoneal lavage and drainage were performed, and a colostomy was created. The patient was managed in the intensive care unit until postoperative day 13 due to septic shock and acute renal failure. After the peritonitis resolved, radiation therapy alone was provided, and then chemotherapy was started to treat residual lesions. Pyometra recurred, and transvaginal drainage was performed to prevent perforation of the uterus. However, a few days later, a colouterine fistula and an enterocutaneous fistula developed simultaneously, and her general condition worsened. In advanced cervical cancer complicated by pyometra, various complications can develop that are difficult to manage (e.g., uterine perforation and fistula formation due to radiation enteritis and dermatitis). This case demonstrates the importance of uterine drainage at appropriate timing, which can contribute to improved prognosis.
