Influencing Factors of HIV/ AIDS Death Based on Bayesian Cox Proportional Hazard Regression Model
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2023.0206
- VernacularTitle:基于贝叶斯Cox风险比例回归的兰州市HIV感染者/AIDS患者死亡影响因素分析
- Author:
Li SHAO
1
;
Ji-jun CHEN
2
;
Kai BAO
3
;
Yu-qi ZHANG
3
;
Jing XU
2
;
Wen-long GAO
3
Author Information
1. Key Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region， School of Medicine， Xizang Minzu University， Xianyang 712082， China
2. Institute of STD and AIDS Prevention and Control， Lanzhou Municipal Center for Disease Control and Prevention， Lanzhou 730030， China
3. Institution of Epidemiology and Health Statistics， School of Public Health， Lanzhou University， Lanzhou 730000， China
- Publication Type:Journal Article
- Keywords:
Cox proportional hazard regression model;
AIDS;
death;
influencing factors
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2023;44(2):224-231
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo understand the composition of related characteristics of HIV/AIDS cases in Lanzhou and analyze the influencing factors of AIDS-related deaths. MethodsThe information of HIV/AIDS cases reported in Lanzhou from 2011 to 2019 was collected， the method of survival was used analysis and Bayesian Cox Proportional Hazard Regression Model was constructed to analyze the related factors of death. ResultsA total of 2 312 HIV/AIDS patients were selected in this study， including 45 AIDS-related deaths. The results of multivariate regression showed that the older the patients were， the higher the risk of death was； the risk of death of AIDS patients at the time of diagnosis was 13.91 times higher than that of HIV-infected patients； Patients who received CD4 testing had a lower risk of death than those who did not； The risk of death was 0.22 times higher among those who received antiretroviral therapy than those who did not receive antiretroviral therapy. ConclusionsAge at diagnosis， course of disease， antiviral therapy were the influencing factors of AIDS-related death in HIV/AIDS patients in Lanzhou. Therefore， it is necessary to strengthen health education for AIDS-related groups， advocate early detection， early diagnosis， and early treatment， expand the coverage of AIDS testing and treatment， prolong the survival time of AIDS patients.
