Changes of T-lymphocyte Subsets Associated with Metabolic Syndrome in the Aged
- VernacularTitle:老年人代谢综合征对淋巴细胞亚群的影响
- Author:
Xiaoyan WU
;
Yi LU
;
Xiaomei SHI
- Publication Type:Journal Article
- Keywords:
metabolic syndrome, immunity, lymphocyte
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(5):424-426
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of subtypes of the lymphocytes with metabolic syndrome in the aged.Methods 955 aged male and 150 aged female were recruited to a cross-sectional case-control study.CD3+,CD4,CD8+,CD19+,NK cell was measured with flow cytometry.ResultsCD3+,CD19+,NK cells showed no difference in cases and in controls.CD4+/CD8+ ratio declined in subjects with metabolic syndrome,and the ratio declined further with the more criteria.The analysis of multiple analysis regression showed that metabolic syndrome depressed CD4+/CD8+ ratio in the aged.Conclusion Metabolic syndrome was correlated with the disorder of immunity.
