Autism spectrum disorder s sensory characteristics and its correlation with core phenotype
10.16835/j.cnki.1000-9817.2023.03.005
- VernacularTitle:孤独症谱系障碍儿童感觉特征及与核心表型的关联
- Author:
ZHAI Jinhe, LI Xiaoxue, XU Zihan, HAO Haiying, XIA Wei, FAN Lili, TENG Wanmeng, WANG Jia
1
Author Information
1. Department of Children s and Adolescent Health,Public Health College, Harbin Medical University, Harbin (150081) , China
- Publication Type:Journal Article
- Keywords:
Autistic disorder;
Sensation;
Signs and symptoms;
Child
- From:
Chinese Journal of School Health
2023;44(3):339-343
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the differences of sensory manifestations between ASD children and typical development children, and to clarify the characteristics of sensory abnormalities in ASD and their relationship with various clinical symptoms, so as to provide scientific basis for early identification and specific intervention.
Methods:A total of 265 ASD children who received rehabilitation training in autism rehabilitation institutions in Heilongjiang Province were collected as the case group, and 223 typical development children in ordinary kindergartens and schools in Harbin were taken as the control group. Short Sensory Profile (SSP) was used to evaluate the difference of children s sensory perception level between the two groups, and Social Response Scale (SRS) and Autism Behavior Checklist (ABC) were used to evaluate the severity of symptoms including social disorder of autistic children. The correlation between SSP scores in ASD group and clinical scales was analyzed.
Results:The comparison of SSP scores between the two groups found that the median scores of all sensory dimensions in ASD group (tactile=33, taste/smell=18, motion sensitivity=13, Low response/sensation seeking=28, auditory filtering=19, low strength=22, visual/auditory=20) were lower than those of the healthy control group( Z =-2.73,-4.36,-3.17,-5.09,-11.00,-10.45,-3.43, P <0.05). The abnormal rate of multisensory score in children in ASD group was 55.1%, and that in control group was 21.2%, with significant difference( χ 2=57.15, P <0.05). Correlation analysis showed that SSP score in ASD group was negatively correlated with all dimensions of SRS, nonverbal communication, and social function of ADI-R scale, ADOS communication and social interaction, and total scores of ABC and CARS( P < 0.05 ).
Conclusion:Children with ASD have atypical sensory experiences, especially in auditory filtering dimension, and the level of atypical sensation is related to the severity of clinical symptoms of autism. In the future clinical diagnosis, treatment and research, it is necessary to strengthen the ability to recognize the sensory symptoms of children with ASD, so as to realize the early diagnosis and intervention.
