Structural characteristics and antitumor activity of polysaccharides from Cordyceps species
10.16438/j.0513-4870.2022-0670
- VernacularTitle:虫草多糖的结构特征及其抗肿瘤活性
- Author:
Zhong-gen ZHAN
;
Su-dan YE
;
Wei-su HUANG
- Publication Type:Research Article
- Keywords:
polysaccharides from Cordyceps species;
structural characteristics;
antitumor activity;
immunomodulatory;
apoptosis
- From:
Acta Pharmaceutica Sinica
2023;58(2):285-297
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharides is one of the main bioactive components of Cordyceps species, because of the potential clinical value with stronger anti-tumor, such as anti-neuroblastoma, anti-melanoma, anti-lung cancer, anti-colon cancer and so on, its have received widespread attention in biomedical field and increasing research in last decades. According to structural elucidation, this review gives a systematic literature overview on antitumor mechanism of Cordyceps species-derived polysaccharides from three aspects, including inhibition of tumor cell growth, enhancement of immunomodulatory activity and reduction of tumor metastasis. Finally, it also puts forward some scientific problems for follow up research.
