Experimental analysis of clinical applicability of individualized customized materials
10.13491/j.issn.1004-714X.2022.05.015
- VernacularTitle:个体化定制材料的临床可应用性实验分析
- Author:
Yun WANG
1
;
Peihua GU
1
;
Jiehua WANG
1
;
Jinlan GONG
1
;
Li CHEN
2
;
Yanshu MU
2
;
Xiaoxiao ZHANG
2
;
Chang GUAN
2
;
Lu WANG
2
Author Information
1. Department of Radiotherapy, Shanghai Shidong Hospital, Shanghai 200438 China.
2. Department of Radiotherapy, Anshan Cancer Hospital, Anshan 114000 China.
- Publication Type:Journal Article
- Keywords:
Individual customization;
Alternative compensation;
Superficial tumor;
3D printing technology
- From:
Chinese Journal of Radiological Health
2022;31(5):601-605
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the feasibility of clinical application of an individualized customized material. Methods Five batches of individualized customized materials were randomly selected, from which 10 cm × 11 cm samples were intercepted for experimental analysis. Among them, 10 cm × 10 cm materials were selected to perform dosimetric analysis and HU change analysis before and after irradiation with a radiotherapy dose for breast cancer of 50 Gy as the irradiation basis. The center Point 1 on the lower surface of the individualized material and the center Point 2 of the solid water volume were selected for dosimetric analysis before and after the sample is irradiated. After reaching a sufficient amount of irradiation, the 1 cm × 10 cm materials intercepted in the center position and the remaining 1 cm × 10 cm materials after the first sampling were sent to the material science laboratory for analysis of physical properties of density, viscosity, hardness, and tear strength. Results In the comparative analysis of HU values before and after exposure, after receiving 50 Gy dose irradiation, the difference rate of HU value was 5.252%, which was close to the expected 5% difference rate in clinical medicine. In the dosimetric analysis of Point 1 and Point 2, the dose in the irradiated samples was significantly higher than that in the unirradiated samples; the dose in Point 1 increased by 3.742%, and the dose in Point 2 increased by 2.039%. Before and after irradiation, except for the physical density which showed a significant difference, there was no significant difference in viscosity, hardness, and tear strength. Conclusion The individualized customized material can meet the requirements of routine clinical medicine.
