Progress in research on pyroptosis and its role in hepatocellular carcinoma
- VernacularTitle:细胞焦亡及其在肝细胞癌中作用的研究进展
- Author:
CHANG Yu⁃ling
1
;
NIU Ya⁃qian CHEN Che
Author Information
- Publication Type:Journal Article
- From: Chinese Journal of Biologicals 2023;36(1):124-127
- CountryChina
- Language:Chinese
- Abstract: Abstract：Pyroptosis is a new programmed cell death mode，which plays a dual role in the pathogenesis of hepatocellular carcinoma（HCC）. On the one hand，inflammasomes causing pyroptosis and inflammatory mediators released during cell pyroptosis promote the occurrence and development of HCC；On the other hand，pyroptosis can inhibit the proliferation， metastasis and invasion of HCC cells. With the deepening of research，the role of pyroptosis in HCC has become increasingly prominent. This paper reviews the potential effects of pyroptosis on the progression of HCC and its role in anticancer therapy. Keywords：Pyroptosis；Inflammasome；Hepatocellular carcinoma（HCC）；Gasdermin D（GSDMD）
- Full text:细胞焦亡及其在肝细胞癌中作用的研究进展.pdf
