Effect evaluation of various nanofiltration systems for filtering intravenous human immunoglobulin
10.13200/j.cnki.cjb.003804
- VernacularTitle:不同纳米过滤系统过滤静注人免疫球蛋白的效果评价
- Author:
MA Li
;
LI Guan⁃jun
;
ZHANG Xue⁃cheng
;
FAN Bei
;
MA Xiao⁃wei
;
WANG Zhi⁃gang
- Publication Type:Journal Article
- From:
Chinese Journal of Biologicals
2023;36(1):81-84
- CountryChina
- Language:Chinese
-
Abstract:
Abstract: Objective To evaluate the filtration effects of various nanofiltration systems on intravenous human immunog⁃
lobulin(IVIG)in order to screen the optimal nanofiltration system. Methods Various nanofilters were used for IVIG
filtration to determine the best one and then various prefilters were selected to combine with the optimal nanofilter for IVIG
filtration to determine the optimal nanofiltration system. Results The tangential flow(cross flow)nanofilter showed better
filtering effect than dead end(direct current)nanofilter,and nanofilter C was the best one. The effect of deep filtration
prefilter was better than that of absolute filtration prefilter,and prefilter Y1 in series with nanofilter C was the optimal
nanofiltration system. Conclusion The optimal nanofiltration system was determined through the effect evaluation of various
nanofiltration systems filtering for IVIG.
- Full text:不同纳米过滤系统过滤静注人免疫球蛋白的效果评价.pdf