Analysis of measles antibody level and susceptibility of enterprise employees in Jinshan District，Shanghai in 2019
10.13200/j.cnki.cjb.003790
- VernacularTitle:2019年上海市金山区企业人群的麻疹抗体水平及易感性分析
- Author:
ZHOU Jie
;
MA Xiao⁃min
;
WANG Fang
;
LI Shu⁃hua
- Publication Type:Journal Article
- Keywords:
Measles；Antibodies；Susceptibility；Enterprise employees
- From:
Chinese Journal of Biologicals
2023;36(1):65-69
- CountryChina
- Language:Chinese
-
Abstract:
Abstract：Objective To analyse the level of measles antibody and serological susceptibility of the enterprise employees in Jin⁃
shan District，Shanghai in 2019，to provide references for measles prevention and control of enterprise employees. Methods
A total of 1 796 employees were selected from 6 enterprises in Jinshan District by using a stratified random sampling method，of
which serum samples from intravenous blood were collected and determined for IgG antibody level of measles by ELISA. Geo⁃
metric mean concentration（GMC）of measles IgG antibody，antibody positive rate and antibody protection rate were calculated
and the susceptibility factors of measles in enterprise employees were analyzed by using the unconditional multivariate Logistic
regression model. Results The GMC of measles antibody in 1 796 monitoring objects was 639. 71 mIU／mL，the positive rate
was 87. 58% and the protection rate was 29. 06%. Multivariate Logistic regression analysis showed that the odds ratio（OR）of
measles susceptibility was 1. 55（95% CI：1. 14 ~ 2. 12）in native subjects compared with non⁃resident subjects，while 2. 35
（95% CI：1. 35 ~ 4. 08）in subjects aged 40 ~ 49 years compared with those aged ≥ 50 years. Conclusion In 2019，the
measles antibody level of enterprise employees in Jinshan District of Shanghai was low，and people aged 40 ~ 49，especially the
nativeadults，wereathighriskofsusceptibilitytomeasles. Supplementaryimmunizationwithmeaslesvaccineshouldbecarried
out for high⁃risk enterprise employees to reduce the risk of measles infection and control the epidemic situation of measles.
- Full text:2019年上海市金山区企业人群的麻疹抗体水平及易感性分析.pdf
