Application of metabonomics in breast cancer
10.12206/j.issn.2097-2024.202109112
- VernacularTitle:代谢组学在乳腺癌诊疗中应用的研究进展
- Author:
Xiaoyu MA
1
;
Caiping LUO
1
;
Yue LIU
2
,
3
Author Information
1. Department of Pharmaceutical Analysis, School of Pharmacy, Naval Medical University, Shanghai 200433, China.
2. Department of Pharmaceutical Analysis, School of Pharmacy, Naval Medical University, Shanghai 200433, China
3. Shanghai Key Laboratory of TCM Metabolites Research, Shanghai 200433, China.
- Keywords:
metabolomics;
breast cancer;
biological biomarkers;
early diagnosis;
drug efficacy evaluation;
disease prognosis
- From:
Journal of Pharmaceutical Practice
2023;41(3):139-145
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a kind of malignant tumor discovered lately, with a high incidence and a poor prognosis. The shortage of relevant biological biomarkers lead to the unsatisfactory treatment efficacy and the early diagnosis in breast cancer. Metabolomics is a new discipline that uses high-throughput analysis techniques to study the dynamic changes of endogenous metabolites under the influence of different pathological physiological stimulation or gene mutations, which has provided a novel way for biomarker screening and disease diagnosis and treatment. The overview of metabolomics and its applications in breast cancer early diagnosis, drug efficacy evaluation, and disease prognosis were summarized in this review.
