Progress in preparation and application of biomimetic nano carriers for cell membrane
10.12206/j.issn.2097-2024.202202058
- VernacularTitle:细胞膜仿生纳米载体的制备及应用研究进展
- Author:
Yu DAI
1
;
Hongbo WANG
1
;
Kangqing BIAN
1
;
Lingyi GUO
1
;
Yuan YU
1
Author Information
1. Department of Pharmaceutics, School of Pharmacy, Naval Medical University, Shanghai 200433, China.
- Keywords:
cell membrane;
biomimetic nanocarriers;
drug delivery system;
biomaterials
- From:
Journal of Pharmaceutical Practice
2023;41(3):135-138
- CountryChina
- Language:Chinese
-
Abstract:
Nanocarriers prepared from organic or inorganic materials are widely used in drug targeting system and diagnosis and treatment of disease. However, there are some problems, such as poor targeting, short circulation time in vivo and improvement in the biocompatibility. Biomimetic nanocarriers has carried out research on the issues, which based on different kinds of cell membrane for the nanocarriers modification, endogenous biofilm improving the biocompatibility of carriers in vivo, more accurate targeting, and even producing immunotherapeutic effect. The principle, method, targeting mechanism and therapeutic effect of biomimetic nano carrier technology of cell membrane have been reviewed in this paper, which provide a new direction for the research of new drug delivery system.
